Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19212145 | 0.89 | GRM5 (0.45) | MEN1KMT2AL3MBTL1GRM5ALDH1A1 | |
| SCHEMBL28683499 | 0.88 | BACE1 (0.47) | BACE1MEN1KMT2AP2RX7SLC2A1 | |
| SCHEMBL29576850 | 0.85 | ABCB1 (0.42) | MEN1KMT2AKEAP1NFE2L2ABCB1 | |
| SCHEMBL21457808 | 0.85 | ABCB1 (0.42) | MEN1KMT2AKEAP1NFE2L2ABCB1 | |
| SCHEMBL28697404 | 0.85 | ABCB1 (0.43) | ABCB1L3MBTL1MAPTSIGMAR1 | |
| SCHEMBL29707390 | 0.85 | BACE1 (0.46) | BACE1MEN1KMT2AP2RX7SLC2A1 | |
| SCHEMBL28673972 | 0.84 | LMNA (0.46) | MEN1KMT2AKEAP1NFE2L2L3MBTL1 | |
| SCHEMBL29707321 | 0.82 | ABCB1 (0.39) | KEAP1NFE2L2ABCB1L3MBTL1LMNA | |
| SCHEMBL21457818 | 0.82 | BACE1 (0.48) | BACE1MEN1KMT2AP2RX7SLC2A1 | |
| SCHEMBL28697188 | 0.81 | PDK4 (0.45) | KEAP1NFE2L2ABCB1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071560-B | Thienopyridine carboxamides as ubiquitin-specific protease inhibitors | 瓦洛健康公司 | 2022-01-14 | — | — | CN | disclosed |