Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 6/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28703440 | 0.73 | MEN1 (0.44) | BDKRB1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4476428 | 0.73 | CYP2D6 (0.38) | NPY2RCYP2D6KCNH2HRH3 | |
| SCHEMBL18440482 | 0.69 | NPY2R (0.33) | NPY2RCYP2D6KCNH2HRH3 | |
| SCHEMBL21383546 | 0.69 | CYP2D6 (0.33) | NPY2RMEN1KMT2ACYP2D6KCNH2 | |
| SCHEMBL28684077 | 0.69 | MAPT (0.39) | BDKRB1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL5765556 | 0.69 | CYP2D6 (0.55) | MEN1KMT2ACYP2D6KCNH2HRH3 | |
| SCHEMBL4465716 | 0.68 | CYP2D6 (0.34) | NPY2RCYP2D6KCNH2HRH3 | |
| SCHEMBL28405167 | 0.68 | LMNA (0.36) | NPY2RCYP2D6KCNH2HRH3SMN1; SMN2 | |
| SCHEMBL18440743 | 0.67 | L3MBTL3 (0.34) | SMN1; SMN2 | |
| SCHEMBL3270029 | 0.67 | SMN1; SMN2 (0.39) | NPY2RCYP2D6KCNH2HRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949558-B | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2022-03-15 | — | — | CN | disclosed |