Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | CPN1 | P15169 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18469974 | 0.84 | HTR1A (0.36) | OPRD1LMNACHRM3TSHR | |
| SCHEMBL18440594 | 0.77 | CCR5 (0.40) | OPRD1CPN1CPB2LMNAPDK2 | |
| SCHEMBL18469990 | 0.76 | ARG1 (0.32) | OPRD1TSHR | |
| Hydrochloric Acid SCHEMBL18428967 | 0.74 | GNAI3 (0.33) | TSHR | |
| SCHEMBL5765556 | 0.72 | CYP2D6 (0.55) | CYP2D6KCNH2HRH3EPHX2HSD11B1 | |
| Hydrochloric Acid SCHEMBL29034671 | 0.70 | CYP2D6 (0.53) | CYP2D6KCNH2HRH3EPHX2HSD11B1 | |
| SCHEMBL21597922 | 0.70 | PIN1 (0.36) | OPRD1CPN1CPB2LMNAPDK2 | |
| SCHEMBL4476428 | 0.69 | CYP2D6 (0.38) | NPY2RCYP2D6KCNH2HRH3EPHX2 | |
| SCHEMBL18440517 | 0.69 | LMNA (0.37) | NPY2RCYP2D6KCNH2HRH3EPHX2 | |
| SCHEMBL28697491 | 0.69 | NPY2R (0.34) | NPY2RCYP2D6KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949558-B | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2022-03-15 | — | — | CN | disclosed |
| EP-3331869-A1 | MUSCARINIC AGONISTS | Heptares Therapeutics Limited (GB) | 2018-06-13 | — | — | EP | disclosed |
| WO-2017021730-A1 | MUSCARINIC AGONISTS | HEPTARES THERAPEUTICS LIMITED (GB) | 2017-02-09 | — | — | WO | disclosed |