Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | RCOR1 | Q9UKL0 | 4/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2635237 | 0.93 | KDM1A (0.60) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL3545211 | 0.83 | KDM1A (0.60) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL3545210 | 0.83 | KDM1A (0.60) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL13009519 | 0.82 | ROCK2 (0.50) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL7985522 | 0.82 | KDM1A (0.59) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL13009693 | 0.82 | NPC1 (0.45) | KDM1AMAOAMAOBRCOR1NPC1 | |
| SCHEMBL2635332 | 0.81 | KDM1A (0.65) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL2635334 | 0.81 | KDM1A (0.65) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL2635331 | 0.81 | KDM1A (0.65) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL13009665 | 0.80 | KDM1A (0.57) | KDM1AMAOAMAOBRCOR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |