Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.60 |
| ▸ | MAOA | P21397 | 2/20 | 0.60 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3545210 | 1.00 | KDM1A (0.60) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL13009665 | 0.90 | KDM1A (0.57) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL28697724 | 0.83 | KDM1A (0.62) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL2635332 | 0.82 | KDM1A (0.65) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL2635334 | 0.82 | KDM1A (0.65) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL2635331 | 0.82 | KDM1A (0.65) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL3297347 | 0.81 | IDO1 (0.60) | IDO1DGAT1 | |
| SCHEMBL3297351 | 0.81 | IDO1 (0.60) | IDO1DGAT1 | |
| SCHEMBL13009667 | 0.81 | HRH3 (0.52) | KDM1AMAOAMAOBRCOR1HRH3 | |
| SCHEMBL24890394 | 0.80 | KDM1A (0.55) | KDM1AMAOAMAOBRCOR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100317653-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | ASTRAZENECA AB (SE) | 2010-12-16 | — | — | US | disclosed |
| US-7795283-B2 | Oxadiazole derivative as DGAT inhibitors | ASTRAZENECA AB (SE) | 2010-09-14 | — | — | US | disclosed |
| US-20080096874-A1 | Oxadiazole Derivative as Dgat Inhibitors | ASTRAZENECA AB (SE) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317653-A1 | OXADIAZOLE DERIVATIVES AS DGAT INHIBITORS | DGAT1, DGAT2, GPR119 | KDM1A 3388/4885MAOA 1483/4885MAOB 1003/4885 |
| US-20080096874-A1 | Oxadiazole Derivative as Dgat Inhibitors | DGAT1, DGAT2, GPR119 | KDM1A 3013/4885MAOA 1463/4885MAOB 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.