Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697806 | 1.00 | TAS1R3 (0.52) | TAS1R3TAS1R1MEN1KMT2ACTSK | |
| SCHEMBL28703116 | 0.88 | TAS1R3 (0.50) | TAS1R3TAS1R1MEN1KMT2ACTSK | |
| SCHEMBL29368864 | 0.87 | TAS1R3 (0.61) | TAS1R3TAS1R1MEN1KMT2ACTSK | |
| SCHEMBL27175282 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ACTSK | |
| SCHEMBL22441334 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ACTSK | |
| SCHEMBL27175279 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ACTSK | |
| SCHEMBL29368573 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ACTSK | |
| SCHEMBL22441335 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1MEN1KMT2ACTSK | |
| SCHEMBL28678223 | 0.87 | MGLL (0.51) | TAS1R3TAS1R1GAAMAPT | |
| SCHEMBL22441253 | 0.84 | TAS1R3 (0.52) | TAS1R3TAS1R1MEN1KMT2ACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008024-A | Compounds having iron death inducing activity and methods of using the same | 费罗治疗公司 | 2022-02-01 | — | — | CN | disclosed |