Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LATS1 | O95835 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.34 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29601605 | 0.75 | KCNH2 (0.39) | ATMKDM4EMAPTCASP1CASP7 | |
| SCHEMBL22819395 | 0.75 | KCNH2 (0.39) | ATMKDM4EMAPTCASP1CASP7 | |
| SCHEMBL22819485 | 0.66 | TLR8 (0.47) | KDM4ECTNNB1TCF7L2 | |
| SCHEMBL29601645 | 0.66 | TLR8 (0.47) | KDM4ECTNNB1TCF7L2 | |
| SCHEMBL22819408 | 0.61 | ALDH1A1 (0.50) | KDM4EMAPTHSD17B10 | |
| SCHEMBL3368672 | 0.61 | EPHX1 (0.59) | — | |
| Hydrochloric Acid SCHEMBL15559762 | 0.60 | EPHX1 (0.46) | — | |
| SCHEMBL11038406 | 0.60 | BID (0.46) | KDM4EMAPTCASP1CASP7HSD17B10 | |
| SCHEMBL1025186 | 0.59 | MAPK1 (0.59) | — | |
| SCHEMBL1022068 | 0.59 | MAPK1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114008029-A | Quinazoline prodrugs for the treatment of viral infections and additional diseases | 爱尔兰詹森科学公司 | 2022-02-01 | — | — | CN | disclosed |