Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | KIT | P10721 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
| ▸ | CCND1 | P24385 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26087273 | 0.89 | ALDH1A1 (0.48) | KDRKITFLT3HSD17B10CRHBP | |
| SCHEMBL30302621 | 0.86 | ALDH1A1 (0.46) | KDRKITFLT3HSD17B10CRHBP | |
| SCHEMBL25421508 | 0.82 | ALDH1A1 (0.43) | KDRHSD17B10CYP3A4TDP1TAAR1 | |
| Benzene SCHEMBL29177892 | 0.81 | ALDH1A1 (0.46) | KDRHSD17B10ALDH1A1CDK4CCND1 | |
| SCHEMBL5887704 | 0.81 | ALDH1A1 (0.46) | KDRHSD17B10ALDH1A1CDK4CCND1 | |
| SCHEMBL28390018 | 0.80 | PRKCZ (0.50) | KDRKITFLT3PRKCZHSD17B10 | |
| Biphenyl SCHEMBL29177817 | 0.79 | ALDH1A1 (0.45) | KDRHSD17B10ALDH1A1CDK4CCND1 | |
| SCHEMBL24079029 | 0.79 | KEAP1 (0.59) | KDRKITFLT3PRKCZHSD17B10 | |
| SCHEMBL19847537 | 0.79 | KIT (0.54) | KDRKITFLT3PRKCZHSD17B10 | |
| SCHEMBL5712565 | 0.79 | HSD17B10 (0.57) | FLT3PRKCZHSD17B10CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116970135-A | Hollow spherical two-dimensional covalent organic framework and preparation method and application thereof | 中国科学院化学研究所 | 2023-10-31 | — | — | CN | disclosed |
| CN-114133502-A | Two-dimensional hetero-pore covalent organic framework compound and preparation method thereof | 江南大学 | 2022-03-04 | — | — | CN | disclosed |
| CN-105741796-B | Liquid crystal display and driving method thereof | 三星显示有限公司 | 2019-12-10 | — | — | CN | disclosed |