Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30253497 | 1.00 | SIRT6 (0.33) | SIRT6APPBACE1IKBKB | |
| SCHEMBL28691237 | 0.87 | IKBKB (0.39) | SIRT6IKBKB | |
| SCHEMBL30253592 | 0.87 | IKBKB (0.39) | SIRT6IKBKB | |
| SCHEMBL28644566 | 0.84 | SIRT6 (0.36) | SIRT6IKBKB | |
| SCHEMBL28707295 | 0.83 | CHEK2 (0.38) | SIRT6APPBACE1IKBKB | |
| SCHEMBL30253749 | 0.83 | CHEK2 (0.38) | SIRT6APPBACE1IKBKB | |
| SCHEMBL28639557 | 0.83 | LMNA (0.36) | SIRT6 | |
| SCHEMBL28652992 | 0.82 | MAPT (0.41) | — | |
| SCHEMBL28685074 | 0.81 | MAPT (0.39) | SIRT6IKBKB | |
| SCHEMBL28658057 | 0.81 | MAPT (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113336713-A | Preparation method of alkoxy pyrazine derivative and alkoxy pyrazine derivative | 中国人民解放军军事科学院军事医学研究院 | 2021-09-03 | — | — | CN | claimed |
| CN-113336713-B | Preparation method of alkoxy pyrazine derivative and alkoxy pyrazine derivative | 中国人民解放军军事科学院军事医学研究院 | 2023-03-17 | — | — | CN | disclosed |
| CN-113336713-A | Preparation method of alkoxy pyrazine derivative and alkoxy pyrazine derivative | 中国人民解放军军事科学院军事医学研究院 | 2021-09-03 | — | — | CN | disclosed |