Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 11/20 | 0.65 |
| ▸ | DRD2 | P14416 | 7/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | DRD5 | P21918 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8688812 | 0.81 | DRD3 (1.00) | DRD3DRD2HTR1A | |
| SCHEMBL28699255 | 0.80 | DRD3 (0.77) | DRD3DRD2HTR1A | |
| SCHEMBL29362760 | 0.79 | DRD3 (0.75) | DRD3DRD2HTR1A | |
| SCHEMBL4047168 | 0.77 | DRD3 (0.77) | DRD3DRD2HTR1A | |
| SCHEMBL16299407 | 0.74 | DRD3 (0.85) | DRD3DRD2HTR1A | |
| SCHEMBL8044371 | 0.73 | DRD3 (0.86) | DRD3DRD2DRD4DRD1HTR2A | |
| SCHEMBL8044410 | 0.70 | HTR1A (0.78) | DRD3DRD2HTR1A | |
| SCHEMBL31558065 | 0.70 | HTR1A (1.00) | DRD3DRD2HTR1ADRD4DRD1 | |
| SCHEMBL9359278 | 0.70 | HTR1A (1.00) | DRD3DRD2HTR1ADRD4DRD1 | |
| SCHEMBL9285858 | 0.69 | DRD3 (0.74) | DRD3DRD2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979915-B | Dopamine D 2 Receptor dual ligand compounds and uses | 常州大学 | 2023-07-25 | — | — | CN | disclosed |
| CN-113979915-A | Dopamine D2Receptor dibit ligand type compound and application | 常州大学 | 2022-01-28 | — | — | CN | disclosed |