Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 1.00 |
| ▸ | DRD3 | P35462 | 11/20 | 0.77 |
| ▸ | DRD2 | P14416 | 11/20 | 0.66 |
| ▸ | DRD4 | P21917 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | HTR7 | P34969 | 2/20 | 0.64 |
| ▸ | DRD1 | P21728 | 1/20 | 0.64 |
| ▸ | DRD5 | P21918 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HTR1D | P28221 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359278 | 1.00 | HTR1A (1.00) | HTR1ADRD3DRD2DRD4MEN1 | |
| Hydrochloric Acid SCHEMBL29064041 | 0.98 | HTR1A (0.97) | HTR1ADRD3DRD2DRD4MEN1 | |
| SCHEMBL8044410 | 0.89 | HTR1A (0.78) | HTR1ADRD3DRD2 | |
| SCHEMBL8688812 | 0.87 | DRD3 (1.00) | HTR1ADRD3DRD2CYP2D6 | |
| SCHEMBL2599112 | 0.87 | HTR1A (0.76) | HTR1ADRD3DRD2DRD4MEN1 | |
| SCHEMBL2599107 | 0.87 | HTR1A (0.76) | HTR1ADRD3DRD2DRD4MEN1 | |
| SCHEMBL13741320 | 0.86 | HTR1A (0.75) | HTR1ADRD3DRD2DRD4 | |
| SCHEMBL8672038 | 0.85 | HTR1A (0.73) | HTR1ADRD3DRD2DRD4MEN1 | |
| SCHEMBL17446163 | 0.85 | HTR1A (0.73) | HTR1ADRD3DRD2DRD4MEN1 | |
| SCHEMBL15323709 | 0.84 | DRD2 (0.76) | HTR1ADRD3DRD2DRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12285426-B2 | Combination serotonin specific reuptake inhibitor and serotonin 1A receptor partial agonist for reducing L-DOPA-induced dyskinesia | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2025-04-29 | — | — | US | disclosed |