Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28689748 | 0.85 | ALDH1A1 (0.54) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22658090 | 0.85 | XDH (0.56) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL29409952 | 0.85 | XDH (0.56) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL22658085 | 0.81 | XDH (0.52) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL29408156 | 0.81 | XDH (0.52) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL22717641 | 0.80 | POLQ (0.45) | KDM4EALDH1A1NPC1RAB9ARORC | |
| SCHEMBL29695103 | 0.80 | POLQ (0.45) | KDM4EALDH1A1NPC1RAB9ARORC | |
| SCHEMBL29694629 | 0.80 | POLQ (0.45) | KDM4EALDH1A1NPC1RAB9ARORC | |
| SCHEMBL28600151 | 0.79 | KDM4E (0.48) | XDHKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL22678610 | 0.78 | ALDH1A1 (0.65) | XDHKDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127049-A | ACSS2 inhibitors and methods of use thereof | 美特波米德有限公司 | 2022-03-01 | — | — | CN | disclosed |