Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 9/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.33 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.33 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.33 |
| ▸ | GRM7 | Q14831 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28984873 | 0.91 | ATM (0.34) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL30474556 | 0.85 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL28692089 | 0.85 | ITGAV (0.49) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL28708238 | 0.77 | ITGB3 (0.57) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL28698397 | 0.74 | ITGAV (0.41) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL20140491 | 0.73 | ITGB3 (0.43) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL29369724 | 0.71 | LMNA (0.40) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL3095932 | 0.71 | FGFR4 (0.40) | FGFR4 | |
| SCHEMBL28337910 | 0.70 | ITGAV (0.40) | ITGAVITGB3ITGB6ITGB5ITGB8 | |
| SCHEMBL29370042 | 0.70 | ITGB3 (0.36) | ITGAVITGB3ITGB6ITGB5ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354635-A | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2021-09-07 | — | — | CN | disclosed |