Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 11/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 11/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15548752 | 0.85 | POLB (0.44) | POLBTDP1NNMTMTNR1AMTNR1B | |
| SCHEMBL30486603 | 0.78 | PDE4A (0.38) | POLBTDP1TXNRD1NNMTMTNR1A | |
| SCHEMBL21383732 | 0.78 | PDE4A (0.38) | POLBTDP1TXNRD1NNMTMTNR1A | |
| SCHEMBL28594753 | 0.77 | KDM4E (0.39) | POLBTDP1TXNRD1NNMTMTNR1A | |
| SCHEMBL30529295 | 0.75 | CYP1A2 (0.37) | POLBTDP1TXNRD1NNMTMTNR1A | |
| SCHEMBL21383820 | 0.75 | CYP1A2 (0.37) | POLBTDP1TXNRD1NNMTMTNR1A | |
| SCHEMBL25679572 | 0.75 | CYP4F2 (0.38) | POLBCYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL20487887 | 0.74 | ALDH1A1 (0.40) | CYP4F2CYP4A11KDM4EALDH1A1MAPT | |
| SCHEMBL8998233 | 0.72 | KDM4E (0.43) | TDP1CYP4F2CYP4A11KDM4EALDH1A1 | |
| SCHEMBL14880583 | 0.72 | MTNR1A (0.65) | TXNRD1MTNR1AMTNR1BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317951-A | Phthalazine derivatives as pyruvate kinase modulators | 西特瑞治疗有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-113354635-B | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-113354635-A | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2021-09-07 | — | — | CN | disclosed |