Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 6/20 | 0.48 |
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28696736 | 0.97 | LDHA (0.52) | LDHAHTTEGFRLMNAMAPK1 | |
| SCHEMBL15684803 | 0.82 | HTT (0.56) | LDHAHTTEGFRLMNAMAPK1 | |
| SCHEMBL28693417 | 0.81 | EGFR (0.62) | HTTEGFRLMNAMAPK1ABCG2 | |
| SCHEMBL28693632 | 0.80 | LDHA (0.52) | LDHAHTTEGFRLMNAMAPK1 | |
| SCHEMBL28674109 | 0.80 | LDHA (0.57) | LDHAHTTEGFRLMNAMAPK1 | |
| SCHEMBL11242436 | 0.80 | LDHA (0.60) | LDHAHTTEGFRLMNAMAPK1 | |
| SCHEMBL17085334 | 0.79 | EGFR (0.58) | HTTEGFRLMNAMAPK1APP | |
| SCHEMBL11250238 | 0.79 | EGFR (0.58) | LDHAHTTEGFRLMNAMAPK1 | |
| SCHEMBL28691836 | 0.79 | GALR3 (0.45) | LDHAHTTEGFRABCG2SMN1; SMN2 | |
| SCHEMBL15684901 | 0.78 | EGFR (0.53) | LDHAHTTEGFRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754636-B | Quinazoline-containing aza-ether compounds | 湖南化工研究院有限公司 | 2022-10-04 | — | — | CN | claimed |
| CN-113754636-A | Quinazoline-containing aza-ether compounds | 湖南化工研究院有限公司 | 2021-12-07 | — | — | CN | claimed |