Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11260593 | 0.82 | PIK3CD (0.71) | EGFRABCG2HTTTSHRLDHA | |
| SCHEMBL11254853 | 0.82 | LDHA (0.67) | EGFRABCG2HTTTSHRLDHA | |
| SCHEMBL11249694 | 0.82 | LDHA (0.64) | EGFRABCG2HTTTSHRLDHA | |
| SCHEMBL11257318 | 0.82 | PIK3CD (0.72) | EGFRHTTLDHAPIK3CDPIK3R1 | |
| SCHEMBL28699733 | 0.79 | LDHA (0.56) | EGFRABCG2HTTTSHRLDHA | |
| SCHEMBL11255679 | 0.79 | LMNA (0.59) | EGFRABCG2HTTLDHAPIK3CD | |
| SCHEMBL11252948 | 0.79 | PIK3CD (0.67) | EGFRABCG2HTTLDHAPIK3CD | |
| SCHEMBL11246622 | 0.79 | PIK3CD (0.66) | EGFRHTTTSHRLDHAPIK3CD | |
| SCHEMBL9430554 | 0.78 | EGFR (0.69) | EGFRABCG2HTTTSHRLMNA | |
| SCHEMBL9609189 | 0.78 | EGFR (0.47) | EGFRABCG2HTTTSHRLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |