Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.58 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GALR3 | O60755 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LIPE | Q05469 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15684803 | 0.90 | HTT (0.56) | EGFRNR2F2POLBGALR3RAB9A | |
| SCHEMBL15684901 | 0.86 | EGFR (0.53) | EGFRNR2F2POLBGALR3RAB9A | |
| SCHEMBL28699733 | 0.79 | LDHA (0.56) | EGFRNR2F2POLBGALR3RAB9A | |
| SCHEMBL15684808 | 0.79 | LMNA (0.47) | EGFRLMNAMAPK1LIPEPLAAT3 | |
| SCHEMBL15684945 | 0.78 | HTT (0.63) | EGFRNR2F2POLBGALR3RAB9A | |
| SCHEMBL28696736 | 0.78 | LDHA (0.52) | EGFRNR2F2POLBGALR3RAB9A | |
| SCHEMBL15684930 | 0.78 | LMNA (0.45) | EGFRLMNAMAPK1LIPECNR1 | |
| SCHEMBL15684933 | 0.76 | LMNA (0.43) | EGFRLMNAMAPK1LIPECNR1 | |
| SCHEMBL9303626 | 0.75 | PLAAT3 (0.48) | EGFRPOLBLMNAMAPK1HTT | |
| SCHEMBL1681345 | 0.75 | EGFR (0.71) | EGFRNR2F2POLBGALR3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2913325-B1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2021-04-21 | — | — | EP | disclosed |
| EP-3760617-A1 | SUBSTITUTED PYRIMIDINE COMPOUND AND USES THEREOF | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2021-01-06 | — | — | EP | disclosed |
| US-9770026-B2 | Substituted pyrimidine compound and uses thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2017-09-26 | — | — | US | disclosed |
| US-9770026-B2 | Substituted pyrimidine compound and uses thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2017-09-26 | — | — | US | disclosed |
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2015-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150257385-A1 | Substituted Pyrimidine Compound and Uses Thereof | TYR, GART, LRRK2 | EGFR 3348/4885NR2F2 3765/4885POLB 1871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.