Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28699794 | 1.00 | RORC (0.55) | RORCKCNH2KDM4ERAB9A | |
| SCHEMBL28715136 | 0.89 | RORC (0.51) | RORCKDM4ERAB9A | |
| SCHEMBL28715139 | 0.89 | RORC (0.51) | RORCKDM4ERAB9A | |
| SCHEMBL28699837 | 0.83 | RORC (0.49) | RORC | |
| SCHEMBL28699838 | 0.83 | RORC (0.49) | RORC | |
| SCHEMBL23631886 | 0.82 | RORC (0.49) | RORCKDM4ERAB9A | |
| SCHEMBL23631889 | 0.82 | RORC (0.49) | RORCKDM4ERAB9A | |
| SCHEMBL28719111 | 0.80 | RORC (0.48) | RORC | |
| SCHEMBL28719108 | 0.80 | RORC (0.48) | RORC | |
| SCHEMBL28936507 | 0.79 | RORC (0.48) | RORCKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075139-A | Five-membered heteroaromatic ring compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-02-22 | — | — | CN | disclosed |