Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 15/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | GIPR | P48546 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28715139 | 1.00 | RORC (0.51) | RORCKDM4ERAB9AGCGRGIPR | |
| SCHEMBL23631889 | 0.91 | RORC (0.49) | RORCKDM4ERAB9AGCGRGIPR | |
| SCHEMBL23631886 | 0.91 | RORC (0.49) | RORCKDM4ERAB9AGCGRGIPR | |
| SCHEMBL28699838 | 0.91 | RORC (0.49) | RORC | |
| SCHEMBL28699837 | 0.91 | RORC (0.49) | RORC | |
| SCHEMBL28699794 | 0.89 | RORC (0.55) | RORCKDM4ERAB9A | |
| SCHEMBL28699796 | 0.89 | RORC (0.55) | RORCKDM4ERAB9A | |
| SCHEMBL28719111 | 0.89 | RORC (0.48) | RORCGCGRGIPRPDE2A | |
| SCHEMBL28719108 | 0.89 | RORC (0.48) | RORCGCGRGIPRPDE2A | |
| SCHEMBL28936509 | 0.87 | RORC (0.48) | RORCKDM4ERAB9AGCGRGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075139-A | Five-membered heteroaromatic ring compound and application thereof in medicines | 广东东阳光药业有限公司 | 2022-02-22 | — | — | CN | disclosed |