Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27489864 | 0.75 | CYP1A2 (0.46) | ALDH1A1LMNAMAPTTSHRMEN1 | |
| SCHEMBL11547067 | 0.74 | MAPT (0.41) | ALDH1A1LMNAMAPTTSHRHSD11B1 | |
| SCHEMBL15043558 | 0.73 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTTSHRHSD11B1 | |
| SCHEMBL548743 | 0.70 | MEN1 (0.42) | ALDH1A1LMNAMAPTTSHRMEN1 | |
| SCHEMBL548545 | 0.70 | NPC1 (0.41) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL549467 | 0.70 | MEN1 (0.39) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9721521 | 0.69 | HSD11B1 (0.42) | ALDH1A1LMNAMAPTTSHRHSD11B1 | |
| SCHEMBL7762417 | 0.68 | MEN1 (0.47) | ALDH1A1LMNAMAPTTSHRMEN1 | |
| SCHEMBL12257921 | 0.68 | KDM1A (0.37) | ALDH1A1LMNAMAPTTSHRHSD11B1 | |
| SCHEMBL14040622 | 0.68 | MEN1 (0.47) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999261-B | O-dimethyl aromatic ring type diphosphine ligand compound and synthesis method thereof | 浙江大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-113999261-A | O-dimethyl aromatic ring diphosphino ligand compound and synthetic method thereof | 浙江大学 | 2022-02-01 | — | — | CN | disclosed |