Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24559595 | 0.78 | MEN1 (0.49) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL22644281 | 0.78 | MEN1 (0.49) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL22644225 | 0.78 | MEN1 (0.49) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL15046513 | 0.77 | RARA (0.43) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL28699951 | 0.73 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTTSHRKMT2A | |
| SCHEMBL27489864 | 0.73 | CYP1A2 (0.46) | ALDH1A1LMNAMAPTTSHRKMT2A | |
| SCHEMBL549467 | 0.71 | MEN1 (0.39) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL548545 | 0.71 | NPC1 (0.41) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL9721521 | 0.71 | HSD11B1 (0.42) | ALDH1A1LMNAMAPTTSHRKMT2A | |
| SCHEMBL22644241 | 0.71 | KDM1A (0.36) | ALDH1A1LMNAKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |