Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28706890 | 1.00 | FOLH1 (0.56) | FOLH1ALDH1A1EPHX1MMEECE1 | |
| SCHEMBL29401534 | 0.92 | ALDH1A1 (0.53) | FOLH1ALDH1A1EPHX1MEN1KMT2A | |
| Cyclopropane SCHEMBL5691187 | 0.91 | FOLH1 (0.65) | FOLH1MMEECE1SIRT2SIRT1 | |
| SCHEMBL1111220 | 0.90 | ALDH1A1 (0.55) | ALDH1A1EPHX1MEN1KMT2ACASP1 | |
| SCHEMBL2928623 | 0.90 | ALDH1A1 (0.55) | ALDH1A1EPHX1MEN1KMT2ACASP1 | |
| Cyclohexylamine SCHEMBL28933270 | 0.89 | FOLH1 (0.56) | FOLH1MMEECE1CASP1 | |
| Cyclohexylamine SCHEMBL28933272 | 0.89 | FOLH1 (0.56) | FOLH1MMEECE1CASP1 | |
| SCHEMBL5144277 | 0.89 | ALDH1A1 (0.59) | ALDH1A1EPHX1MEN1KMT2ACASP1 | |
| SCHEMBL29402502 | 0.88 | ITGB3 (0.49) | FOLH1ALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL910233 | 0.87 | FOLH1 (0.70) | FOLH1MMEECE1CASP1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113321606-A | Preparation method of (S) -1- (benzyloxycarbonyl) -5-oxopyrrolidine-2-formic acid | 吉尔生化（上海）有限公司 | 2021-08-31 | — | — | CN | disclosed |