Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28708142 | 0.89 | NLRP3 (0.52) | NLRP3MEN1MAPTKMT2APOLB | |
| SCHEMBL28704857 | 0.88 | GAA (0.58) | MEN1MAPTKMT2AHTTEPHX2 | |
| SCHEMBL28933287 | 0.87 | MEN1 (0.68) | MEN1MAPTKMT2APOLBNR2E1 | |
| SCHEMBL29389113 | 0.87 | MEN1 (0.68) | MEN1MAPTKMT2APOLBNR2E1 | |
| SCHEMBL28684550 | 0.86 | MEN1 (0.61) | MEN1MAPTKMT2ARORCLMNA | |
| SCHEMBL28698365 | 0.85 | ALDH1A1 (0.52) | NLRP3MEN1MAPTKMT2APOLB | |
| SCHEMBL28684557 | 0.85 | ALDH1A1 (0.57) | NLRP3MEN1MAPTKMT2APOLB | |
| SCHEMBL28933313 | 0.85 | MEN1 (0.54) | NLRP3MEN1MAPTKMT2ALMNA | |
| SCHEMBL28933319 | 0.85 | EPHX2 (0.47) | MEN1MAPTKMT2APOLBRORC | |
| SCHEMBL28698336 | 0.83 | NPC1 (0.62) | MEN1MAPTKMT2APOLBHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | claimed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | claimed |
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | disclosed |