Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28697841 | 0.73 | SCN9A (0.32) | SCN9A | |
| SCHEMBL15875664 | 0.72 | HCAR2 (0.32) | SCN9AALDH1A1KDM4ENPSR1 | |
| SCHEMBL13907508 | 0.71 | APLNR (0.36) | SCN9AFAAHALDH1A1KDM4E | |
| SCHEMBL31639436 | 0.70 | STK17B (0.36) | SCN9AFAAHALDH1A1KDM4ELMNA | |
| SCHEMBL25182441 | 0.69 | APLNR (0.35) | SCN9AALDH1A1KDM4E | |
| SCHEMBL20535616 | 0.69 | APLNR (0.35) | SCN9AALDH1A1KDM4E | |
| SCHEMBL20535201 | 0.69 | APLNR (0.35) | SCN9AALDH1A1KDM4E | |
| SCHEMBL20535618 | 0.69 | APLNR (0.35) | SCN9AALDH1A1KDM4E | |
| SCHEMBL4321251 | 0.68 | CYP2D6 (0.34) | SCN9AFAAHALDH1A1KDM4E | |
| SCHEMBL6688426 | 0.67 | DGAT1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943296-A | Pyrrolopyrimidine derivatives and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-01-18 | — | — | CN | disclosed |