Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875623 | 0.80 | — | — | |
| SCHEMBL15875530 | 0.79 | CYP4F2 (0.36) | HCAR2 | |
| Hydrochloric Acid SCHEMBL28678114 | 0.78 | CYP4F2 (0.36) | HCAR2KDM4EALDH1A1 | |
| SCHEMBL22315715 | 0.76 | HRH3 (0.32) | NPSR1POLB | |
| SCHEMBL22316960 | 0.76 | APLNR (0.31) | ALDH1A1 | |
| SCHEMBL22315716 | 0.76 | APLNR (0.31) | ALDH1A1 | |
| SCHEMBL28697841 | 0.73 | SCN9A (0.32) | LATS1SCN9A | |
| SCHEMBL28701467 | 0.72 | SCN9A (0.35) | SCN9ANPSR1KDM4EALDH1A1 | |
| SCHEMBL13907508 | 0.71 | APLNR (0.36) | LATS1NR1H2SCN9AKDM4EALDH1A1 | |
| SCHEMBL31639436 | 0.70 | STK17B (0.36) | LATS1SCN9ANPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230312582-A1 | Salts Of Nitrogen-Containing Heterocyclic Compound, And Solid Forms Of Salts, Pharmaceutical Composition And Use Thereof | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2023-10-05 | — | — | US | disclosed |
| EP-2943494-B1 | PYRIDO- OR PYRROLO-FUSED PYRIMIDINE DERIVATIVES AS AUTOTAXIN INHIBITORS FOR TREATING PAIN | LILLY CO ELI (US) | 2017-02-22 | — | — | EP | disclosed |
| EP-2943494-B1 | PYRIDO- OR PYRROLO-FUSED PYRIMIDINE DERIVATIVES AS AUTOTAXIN INHIBITORS FOR TREATING PAIN | LILLY CO ELI (US) | 2017-02-22 | — | — | EP | disclosed |
| EP-2943494-A1 | PYRIDO- OR PYRROLO-FUSED PYRIMIDINE DERIVATIVES AS AUTOTAXIN INHIBITORS FOR TREATING PAIN | Eli Lilly and Company (US) | 2015-11-18 | — | — | EP | disclosed |
| US-8969555-B2 | Bicyclic pyrimidine compounds | ELI LILLY AND COMPANY (US) | 2015-03-03 | — | — | US | disclosed |
| US-8969555-B2 | Bicyclic pyrimidine compounds | ELI LILLY AND COMPANY (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140200231-A1 | Bicyclic Pyrimidine Compounds | ELI LILLY AND COMPANY (US) | 2014-07-17 | — | — | US | disclosed |
| WO-2014110000-A1 | PYRIDO- OR PYRROLO-FUSED PYRIMIDINE DERIVATIVES AS AUTOTAXIN INHIBITORS FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 2014-07-17 | — | — | WO | disclosed |
| WO-2014110000-A1 | PYRIDO- OR PYRROLO-FUSED PYRIMIDINE DERIVATIVES AS AUTOTAXIN INHIBITORS FOR TREATING PAIN | ELI LILLY AND COMPANY (US) | 2014-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230312582-A1 | Salts Of Nitrogen-Containing Heterocyclic Compound, And Solid Forms Of Salts, Pharmaceutical Composition And Use Thereof | ATXN10, ATXN2, ATXN2L | HCAR2 4017/4885LATS1 4556/4885NR1H2 4629/4885 |
| US-20140200231-A1 | Bicyclic Pyrimidine Compounds | ENPP2, HAX1, NUDT1 | HCAR2 145/4885LATS1 4733/4885NR1H2 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.