Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28713901 | 0.86 | MAPT (0.37) | HDAC6HDAC3HDAC8HDAC1HDAC2 | |
| SCHEMBL23012822 | 0.80 | HDAC6 (0.37) | HDAC6HDAC3HDAC8HDAC1HDAC2 | |
| SCHEMBL28707209 | 0.79 | MAPT (0.43) | HDAC6HDAC3HDAC8HDAC1HDAC2 | |
| SCHEMBL31165931 | 0.77 | NPC1 (0.46) | KDM4EALDH1A1HPGDHSD17B10PPARG | |
| SCHEMBL23012205 | 0.77 | NPC1 (0.46) | KDM4EALDH1A1HPGDHSD17B10PPARG | |
| SCHEMBL28710788 | 0.68 | NPC1 (0.36) | HDAC6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL28707255 | 0.67 | APP (0.40) | KDM4EALDH1A1MAPTAPP | |
| SCHEMBL28695261 | 0.67 | APP (0.41) | HDAC6APP | |
| SCHEMBL26688000 | 0.67 | RAB9A (0.53) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL26688003 | 0.64 | NPC1 (0.50) | KDM4EALDH1A1HPGDHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |