Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.45 |
| ▸ | GRK5 | P34947 | 8/20 | 0.44 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | GRK2 | P25098 | 7/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31165937 | 0.93 | GRK5 (0.44) | METGRK5ALKGRK2KCNH2 | |
| SCHEMBL28714673 | 0.91 | GRK5 (0.49) | METGRK5GRK2KCNH2 | |
| SCHEMBL28707207 | 0.81 | PIM1 (0.44) | METGRK5ALK | |
| SCHEMBL28935891 | 0.79 | HSPD1 (0.38) | METGRK5 | |
| SCHEMBL31165946 | 0.78 | GRK5 (0.46) | METGRK5ALKGRK2MKNK1 | |
| SCHEMBL28935935 | 0.77 | PIK3CD (0.40) | — | |
| SCHEMBL28701717 | 0.77 | PIK3CD (0.40) | METLRRK2 | |
| SCHEMBL29479792 | 0.76 | GRK5 (0.51) | METGRK5GRK2 | |
| SCHEMBL28713867 | 0.76 | GRK5 (0.51) | METGRK5GRK2 | |
| SCHEMBL28710820 | 0.74 | ACSL1 (0.46) | LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |