SCHEMBL28702008

SCHEMBL28702008

CC(O)C(O)Cc1ccc(F)cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 3/20 0.57
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
HPGD P15428 1/20 0.41
HTT P42858 2/20 0.40
IDO1 P14902 1/20 0.39
LOXL2 Q9Y4K0 1/20 0.39
CPA1 P15085 1/20 0.39
KMT2A Q03164 1/20 0.38
TAAR1 Q96RJ0 4/20 0.38
KDM4E B2RXH2 1/20 0.38
LMNA P02545 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
ALOX15 P16050 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23347539 0.87 TRPA1 (0.62) TRPA1MAOAMAOBHPGDHTT
SCHEMBL19628385 0.83 TRPA1 (0.58) TRPA1MAOAMAOBHPGDHTT
SCHEMBL17892900 0.83 TRPA1 (0.57) TRPA1MAOAMAOBHPGDHTT
SCHEMBL17892897 0.83 TRPA1 (0.57) TRPA1MAOAMAOBHPGDHTT
SCHEMBL14520625 0.82 TRPA1 (0.61) TRPA1MAOAMAOBHPGDHTT
SCHEMBL2172447 0.82 TRPA1 (0.61) TRPA1MAOAMAOBHPGDHTT
SCHEMBL23347630 0.82 TRPA1 (0.61) TRPA1MAOAMAOBHPGDHTT
SCHEMBL107844 0.80 TAAR1 (0.59) TAAR1MAPK1HSD17B10
SCHEMBL28128396 0.79 TRPA1 (0.58) TRPA1MAOAMAOBHPGDLOXL2
SCHEMBL28982569 0.78 ALDH1A1 (0.45) IDO1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114108014-B Method for synthesizing pinacol by selective electroreduction coupling of active hydrogen-mediated carbonyl compound in water 天津大学 2023-08-11 CN claimed
CN-114108014-A Method for synthesizing pinacol by selective electroreduction coupling of carbonyl compound mediated by active hydrogen in water 天津大学 2022-03-01 CN claimed
CN-114108014-B Method for synthesizing pinacol by selective electroreduction coupling of active hydrogen-mediated carbonyl compound in water 天津大学 2023-08-11 CN disclosed
CN-115304773-B Organic polymer semiconductor material, preparation method and application thereof 清华大学 2023-07-25 CN disclosed
CN-115304773-A Organic polymer semiconductor material and preparation method and application thereof 清华大学 2022-11-08 CN disclosed
CN-114108014-A Method for synthesizing pinacol by selective electroreduction coupling of carbonyl compound mediated by active hydrogen in water 天津大学 2022-03-01 CN disclosed