Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23347539 | 0.88 | TRPA1 (0.62) | TRPA1MAOAMAOBHPGDAOC3 | |
| SCHEMBL19628382 | 0.84 | TRPA1 (0.69) | TRPA1MAOAMAOBHPGDAOC3 | |
| SCHEMBL28702008 | 0.83 | TRPA1 (0.57) | TRPA1MAOAMAOBHPGDHTT | |
| SCHEMBL109936 | 0.82 | TAAR1 (0.55) | MAPK1TAAR1 | |
| SCHEMBL20008956 | 0.79 | TRPA1 (0.57) | TRPA1MAOATAAR1 | |
| SCHEMBL105769 | 0.79 | TRPA1 (0.57) | TRPA1MAOATAAR1 | |
| SCHEMBL2172447 | 0.79 | TRPA1 (0.61) | TRPA1MAOAMAOBHPGDHTT | |
| SCHEMBL23347630 | 0.79 | TRPA1 (0.61) | TRPA1MAOAMAOBHPGDHTT | |
| SCHEMBL14520625 | 0.79 | TRPA1 (0.61) | TRPA1MAOAMAOBHPGDHTT | |
| SCHEMBL19628384 | 0.77 | TRPA1 (0.50) | TRPA1MAOAMAOBHPGDAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2017-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334934-A1 | Macrocyclic picolinamides as fungicides | CYP4F12, CYP1A2, FKBP2 | TRPA1 676/4885MAOA 1834/4885MAOB 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.