Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | FLT4 | P35916 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29444021 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL6744997 | 0.86 | TSHR (0.51) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL27598378 | 0.85 | F2R (0.48) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL30702134 | 0.83 | GSK3B (0.52) | ALDH1A1SMN1; SMN2KDM4EFLT1FLT4 | |
| SCHEMBL7779200 | 0.83 | GSK3B (0.52) | ALDH1A1SMN1; SMN2KDM4EFLT1FLT4 | |
| SCHEMBL27604216 | 0.82 | MMP1 (0.43) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL20364210 | 0.81 | FLT1 (0.46) | ALDH1A1SMN1; SMN2KDM4EFLT1FLT4 | |
| SCHEMBL29712843 | 0.81 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL6174178 | 0.81 | HSP90AB1 (0.48) | ALDH1A1SMN1; SMN2KMT2AFLT1FLT4 | |
| SCHEMBL1144066 | 0.81 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117164523-A | Oxo-pyridine compound and preparation method and application thereof | 成都施贝康生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-116768897-A | Tetraazatricyclic compound and preparation method and application thereof | 深圳信立泰药业股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-113929618-B | Oxo-pyridine amide derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-116120240-A | FXIa inhibitor compound, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-113912586-B | Oxopyridine amide derivatives, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114206854-B | FXIa inhibitor and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-02-24 | — | — | CN | disclosed |
| US-20230027295-A1 | FXIA INHIBITORS AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
| US-20230027295-A1 | FXIA INHIBITORS AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | SHENZHEN SALUBRIS PHARMACEUTICALS CO., LTD. (CN) | 2023-01-26 | — | — | US | disclosed |
| CN-111875559-B | Thiazole hydrazide derivatives and application thereof as agricultural bactericide | 南京农业大学 | 2022-11-22 | — | — | CN | disclosed |
| EP-4036087-A1 | FXIA INHIBITORS AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Shenzhen Salubris Pharmaceuticals Co. Ltd (CN) | 2022-08-03 | — | — | EP | disclosed |
| CN-1980664-A | CRTH2 receptor ligands for therapeutic use | 7TM PHARMA AS (DK) | 2007-06-13 | — | — | CN | disclosed |
| CN-1662513-A | 2-thioxothiazole derivative, method for preparing the same, and pharmaceutical composition containing the same | CJ CORP (KR) | 2005-08-31 | — | — | CN | disclosed |
| CN-1210275-C | Respiratory syncytial virus replication inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2005-07-13 | — | — | CN | disclosed |
| CN-1358181-A | Respiratory syncytial virus replication inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2002-07-10 | — | — | CN | disclosed |
| CN-1068000-C | Apolipoprotein-B synthesis inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2001-07-04 | — | — | CN | disclosed |
| CN-1201453-A | 4- (cycloalkyl) -piperidine and 4- (cycloalkylalkyl) piperidine derivatives, their preparation and their use in medicine | SYNTHELABO CO (FR) | 1998-12-09 | — | — | CN | disclosed |
| CN-1162596-A | Antiarrhythmic Agents | AMERICAN CYANAMID CO (US) | 1997-10-22 | — | — | CN | disclosed |
| CN-1161695-A | Apolioprotein-B synthesis inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 1997-10-08 | — | — | CN | disclosed |
| CN-1071420-A | 4-[4-[4-(4-hydroxyphenyl)-1-piperazinyl] phenyl]-5-methyl-3H-1,2,4-triazole-3-ketone derivatives | JANSSEN PHARMACEUTICA NV (BE) | 1993-04-28 | — | — | CN | disclosed |
| EP-0092239-A2 | Oxazole derivatives, production and use thereof | Takeda Chemical Industries, Ltd. (JP) | 1983-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027295-A1 | FXIA INHIBITORS AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | F11, TFPI, F7 | ALDH1A1 3516/4885SMN1; SMN2 4363/4885KDM4E 1793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.