Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 8/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698922 | 0.77 | MEN1 (0.36) | SRCMEN1KMT2A | |
| SCHEMBL28668858 | 0.76 | MEN1 (0.34) | SRCMEN1KMT2A | |
| SCHEMBL29496240 | 0.75 | MEN1 (0.40) | SRCMEN1KMT2A | |
| SCHEMBL1661739 | 0.75 | NR1H2 (0.51) | L3MBTL1NR1H2MEN1KMT2A | |
| SCHEMBL29770673 | 0.74 | NR1H2 (0.46) | NR1H2MEN1KMT2A | |
| SCHEMBL18044508 | 0.74 | HPGD (0.41) | NR1H2MEN1KMT2A | |
| SCHEMBL17686381 | 0.74 | SRC (0.41) | SRCL3MBTL1NR1H2MEN1KMT2A | |
| SCHEMBL21722174 | 0.74 | PARP1 (0.39) | SRCNR1H2MEN1KMT2A | |
| SCHEMBL1900990 | 0.73 | GABRA1 (0.46) | L3MBTL1MEN1KMT2A | |
| SCHEMBL10724223 | 0.73 | GABRA1 (0.46) | L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641898-B | 5, 7-dihydro-pyrrolo-pyridine derivatives for the treatment of neurological and neurodegenerative diseases | 辉瑞公司 | 2022-04-08 | — | — | CN | disclosed |