Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28668858 | 0.78 | MEN1 (0.34) | MEN1KMT2AALDH1A1TSHRSRC | |
| SCHEMBL29496240 | 0.78 | MEN1 (0.40) | MEN1KMT2AALDH1A1TSHRSRC | |
| SCHEMBL28704129 | 0.77 | SRC (0.37) | MEN1KMT2ASRC | |
| SCHEMBL18044508 | 0.73 | HPGD (0.41) | MEN1KMT2AALDH1A1TSHRKDM4E | |
| SCHEMBL9699443 | 0.73 | SRC (0.40) | MEN1KMT2ASRCGLA | |
| SCHEMBL24918246 | 0.73 | HCRTR2 (0.40) | ALDH1A1HCRTR2HPGDHSD17B10 | |
| SCHEMBL30664862 | 0.73 | HCRTR2 (0.40) | ALDH1A1HCRTR2HPGDHSD17B10 | |
| SCHEMBL29222288 | 0.73 | HCRTR2 (0.40) | ALDH1A1HCRTR2HPGDHSD17B10 | |
| SCHEMBL10724223 | 0.73 | GABRA1 (0.46) | MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL1900990 | 0.73 | GABRA1 (0.46) | MEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |