P-Toluenesulfonamide

P-Toluenesulfonamide

SCHEMBL28704205

Cc1ccc(S(N)(=O)=O)cc1.Clc1ccccc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 8/20 0.69
CA2 P00918 8/20 0.69
CA9 Q16790 8/20 0.69
CA12 O43570 7/20 0.69
CA7 P43166 4/20 0.69
CA3 P07451 3/20 0.69
CA6 P23280 3/20 0.69
CA5A P35218 3/20 0.69
CA5B Q9Y2D0 3/20 0.69
CA4 P22748 3/20 0.63
CA13 Q8N1Q1 2/20 0.63
CA14 Q9ULX7 2/20 0.63
PTGS2 P35354 7/20 0.58
PTGS1 P23219 3/20 0.58
PLA2G7 Q13093 1/20 0.56
PTPN7 P35236 1/20 0.50
SOS1 Q07889 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Chlorobenzenesulfonamide SCHEMBL28134053 0.92 CA12 (0.69) CA1CA2CA9CA12CA7
P-Toluenesulfonamide SCHEMBL5691991 0.88 CA2 (0.82) CA1CA2CA9CA12CA7
P-Chlorobenzenesulfonamide SCHEMBL7527510 0.84 CA12 (0.82) CA1CA2CA9CA12CA7
P-Chlorobenzenesulfonamide SCHEMBL28326001 0.83 CA12 (0.90) CA1CA2CA9CA12CA7
P-Toluenesulfonamide SCHEMBL7370 0.83 CA2 (1.00) CA1CA2CA9CA12CA7
P-Toluenesulfonamide SCHEMBL1331323 0.83 CA2 (1.00) CA1CA2CA9CA12CA7
P-Toluenesulfonamide SCHEMBL31527821 0.83 CA2 (1.00) CA1CA2CA9CA12CA7
Benzenesulfonamide SCHEMBL28055374 0.83 CA1 (0.67) CA1CA2CA9CA12CA7
Sulfanilamide SCHEMBL27497104 0.82 CA2 (0.68) CA1CA2CA9CA12CA7
P-Toluenesulfonamide SCHEMBL8376384 0.81 CA2 (0.95) CA1CA2CA9CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181120-A Preparation method of p-toluenesulfonyl isocyanate 寿光诺盟化工有限公司 2022-03-15 CN claimed
CN-114181120-A Preparation method of p-toluenesulfonyl isocyanate 寿光诺盟化工有限公司 2022-03-15 CN disclosed
CN-114181120-A Preparation method of p-toluenesulfonyl isocyanate 寿光诺盟化工有限公司 2022-03-15 CN disclosed