SCHEMBL28705258

SCHEMBL28705258

Cc1ccc(C(C)C)c2nc3ccccc3nc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 5/20 0.42
LMNA P02545 1/20 0.40
MAPT P10636 5/20 0.38
MAPK1 P28482 2/20 0.38
TSHR P16473 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
KDM1A O60341 1/20 0.37
RAB9A P51151 3/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 2/20 0.37
MEN1 O00255 1/20 0.37
HCRTR1 O43613 1/20 0.37
CASR P41180 1/20 0.36
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
DHFR P00374 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL812440 0.83 NQO2 (0.56) NQO2MAPTTDP1RAB9AKMT2A
SCHEMBL20821316 0.80 PDE1A (0.42) LMNAMAPTMAPK1TSHRTDP1
SCHEMBL31447451 0.72 NQO2 (0.42) NQO2LMNAMAPTMAPK1TSHR
SCHEMBL20915022 0.72 NQO2 (0.42) NQO2LMNAMAPTMAPK1TSHR
SCHEMBL20370280 0.70 LMNA (0.41) LMNAMAPTMAPK1KMT2AMEN1
SCHEMBL13193188 0.69 CCR1 (0.37) LMNAKMT2ANPC1MEN1GAA
SCHEMBL5798945 0.69 NQO2 (0.81) NQO2LMNAMAPTMAPK1ATM
SCHEMBL7074871 0.69 NQO2 (0.42) NQO2LMNAMAPTMAPK1TSHR
SCHEMBL183009 0.69 NQO2 (0.57) NQO2LMNAMAPTMAPK1ATM
SCHEMBL10239514 0.68 MEN1 (0.41) LMNAMAPTMAPK1TSHRRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109310082-B Timed release granular agrochemical composition and process for producing the same 拜耳农作物科学股份公司 2022-03-29 CN disclosed