SCHEMBL7074871

SCHEMBL7074871

CCc1ccc(C)c2nc3ccccc3nc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 3/20 0.42
ELANE P08246 2/20 0.40
LMNA P02545 4/20 0.38
MAPT P10636 5/20 0.38
NPC1 O15118 2/20 0.38
HCRTR1 O43613 2/20 0.38
TP53 P04637 2/20 0.38
USP2 O75604 2/20 0.38
TSHR P16473 2/20 0.38
CASP1 P29466 2/20 0.38
CASP7 P55210 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HSD17B10 Q99714 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM1A O60341 1/20 0.37
RAB9A P51151 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
POLB P06746 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL812440 0.83 NQO2 (0.56) NQO2MAPTNPC1HCRTR1KDM4E
SCHEMBL3414003 0.76 NQO2 (0.50) NQO2ELANELMNAMAPTNPC1
Hydrochloric Acid SCHEMBL6769346 0.74 NQO2 (0.48) NQO2ELANELMNAMAPTNPC1
SCHEMBL19242233 0.72 ELANE (0.36) ELANEMAPTTP53KDM4EL3MBTL1
SCHEMBL22351862 0.72 NQO2 (0.45) NQO2LMNAMAPTNPC1HCRTR1
SCHEMBL7894193 0.72 NQO2 (0.42) NQO2LMNAMAPTNPC1HCRTR1
SCHEMBL7567602 0.70 ALDH1A1 (0.61) LMNAMAPTKDM4EALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL28861787 0.70 NQO2 (0.41) NQO2LMNAMAPTNPC1HCRTR1
SCHEMBL17794103 0.69 NOS3 (0.39) ELANELMNANPC1L3MBTL1MEN1
SCHEMBL28705258 0.69 NQO2 (0.42) NQO2LMNAMAPTNPC1HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
EP-0458502-B1 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-18 EP disclosed
EP-0328020-B1 Use of a catalyst in epoxy compositions DOW CHEMICAL CO (US) 1996-10-09 EP disclosed
US-5503937-A MIXTURE OF A COMPOUND HAVING MORE THAN ONE EPOXY GROUP, A DIHYDRIC PHENOLIC COMPOUND AND A LATENT CATALYST COMPRISING A SALT OF AN N-HETEROCYCLIC COMPOUND AND AN ACID HAVING A STRONG NUCLEOPHILIC ANION; COATINGS/MOLDINGS; STORAGE THE DOW CHEMICAL COMPANY (US) 1996-04-02 US disclosed
EP-0553887-A2 Catalysts and epoxy resin composition containing the same THE DOW CHEMICAL COMPANY (US) 1993-08-04 EP disclosed
US-5169473-A Complex of an onium, arsenic or amine compound and boric acid; advanced polyepoxides; storage stability THE DOW CHEMICAL COMPANY (US) 1992-12-08 US disclosed
US-5134239-A Quaterinary indolizine compound THE DOW CHEMICAL COMPANY (US) 1992-07-28 US disclosed
EP-0458502-A2 Latent catalysts, cure-inhibited epoxy resin compositions and laminates prepared therefrom THE DOW CHEMICAL COMPANY (US) 1991-11-27 EP disclosed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US disclosed
EP-0328020-A2 Use of a catalyst in epoxy compositions THE DOW CHEMICAL COMPANY (US) 1989-08-16 EP disclosed