Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 6/20 | 0.46 |
| ▸ | INSR | P06213 | 5/20 | 0.46 |
| ▸ | IGF1R | P08069 | 5/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CCNK | O75909 | 1/20 | 0.39 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31305007 | 0.87 | ALK (0.41) | ALKINSRIGF1RPTK2 | |
| SCHEMBL28689797 | 0.85 | ALK (0.54) | ALKINSRIGF1RPTK2 | |
| SCHEMBL28689800 | 0.84 | ALK (0.45) | ALKINSRIGF1R | |
| SCHEMBL28710017 | 0.84 | PDE4B (0.49) | PDE4BCCNT1CDK9MAPTTP53 | |
| SCHEMBL28710161 | 0.83 | ALK (0.60) | ALKINSRIGF1RPTK2 | |
| SCHEMBL28699319 | 0.82 | ALK (0.45) | ALKINSRIGF1R | |
| SCHEMBL28690880 | 0.79 | ALK (0.48) | ALKINSRIGF1RCDK9PTK2 | |
| SCHEMBL28703587 | 0.78 | PTK2 (0.45) | ALKINSRIGF1RCDK9PTK2 | |
| SCHEMBL28703584 | 0.78 | ALK (0.51) | ALKINSRIGF1RCDK9PTK2 | |
| SCHEMBL25328533 | 0.73 | CDK9 (0.61) | ALKINSRIGF1RCDK9PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181257-A | Pyridine compound, pharmaceutical composition containing pyridine compound, preparation method and application of pyridine compound | 四川科伦博泰生物医药股份有限公司 | 2022-03-15 | — | — | CN | disclosed |