Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15494723 | 0.94 | HSD17B10 (0.59) | THRBLMNAMAPTPOLBPKM | |
| SCHEMBL29261849 | 0.91 | ELANE (0.53) | THRBLMNAMAPTPOLBPKM | |
| SCHEMBL24171804 | 0.89 | THRB (0.50) | THRBLMNAMAPTPOLBPKM | |
| SCHEMBL2587522 | 0.89 | THRB (0.64) | THRBLMNAMAPTPKMELANE | |
| SCHEMBL5899677 | 0.88 | THRB (0.49) | THRBLMNAMAPTPOLBPKM | |
| SCHEMBL19155399 | 0.84 | CA12 (0.49) | THRBLMNAMAPTPOLBKDM4E | |
| SCHEMBL20342948 | 0.83 | THRB (0.45) | THRBLMNAMAPTPOLBPKM | |
| SCHEMBL2583966 | 0.83 | THRB (0.61) | THRBLMNAMAPTPKMELANE | |
| SCHEMBL898885 | 0.83 | MAPT (0.57) | THRBLMNAMAPTPOLBELANE | |
| SCHEMBL269329 | 0.83 | LMNA (0.80) | LMNAMAPTPOLBPKMELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177808-A | Delivery particles with high core to wall ratio | 恩盖普有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-116490536-A | Biodegradable delivery particles | 恩盖普有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116490068-A | Biodegradable delivery particles | 恩盖普有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116471933-A | Biodegradable delivery particles | 恩盖普有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116472303-A | Polyacrylate and poly (beta-ester) capsules with improved degradability | 恩盖普有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-116033963-A | Benefit agent-containing delivery particles with high core-to-wall ratio | 恩盖普有限公司 | 2023-04-28 | — | — | CN | disclosed |
| CN-109651253-B | Phenylpropanoid ester derivative and application thereof as neuroprotective medicament | 上海医药工业研究院 | 2022-03-25 | — | — | CN | disclosed |