Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584694 | 0.93 | THRB (0.54) | THRBMAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL202339 | 0.93 | THRB (0.54) | THRBMAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL15803521 | 0.88 | THRB (0.50) | THRBMAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL15803539 | 0.88 | THRB (0.50) | THRBMAPTPOLBSMN1; SMN2MEN1 | |
| SCHEMBL28705673 | 0.88 | THRB (0.59) | THRBLMNAMAPTPOLBPKM | |
| SCHEMBL5491320 | 0.88 | LMNA (0.59) | LMNAMAPTPOLBPKMSMN1; SMN2 | |
| SCHEMBL10629411 | 0.88 | LMNA (0.59) | LMNAMAPTPOLBPKMSMN1; SMN2 | |
| SCHEMBL16488504 | 0.87 | THRB (0.49) | THRBLMNAMAPTSMN1; SMN2KDM4E | |
| SCHEMBL5899549 | 0.87 | THRB (0.49) | THRBLMNAMAPTPKMSMN1; SMN2 | |
| SCHEMBL644250 | 0.87 | ESR1 (0.53) | THRBLMNAMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787907-B2 | Polyvinyl thioether ester, preparation method therefor and use thereof | SOOCHOW UNIVERSITY (CN) | 2023-10-17 | — | — | US | disclosed |
| US-20060261318-A1 | Light control film | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-11-23 | — | — | US | disclosed |