Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24576336 | 0.79 | GABRA1 (0.37) | MAPTRAB9ALMNAHPGDSMN1; SMN2 | |
| SCHEMBL19007359 | 0.78 | GABRA1 (0.34) | MAPTNPC1RAB9ALMNAHTT | |
| SCHEMBL18851192 | 0.77 | HTR2A (0.36) | CHRNB2CHRNA7CHRNA4HTR2ASLC6A4 | |
| SCHEMBL6650753 | 0.76 | PYCR1 (0.43) | MAPTNPC1RAB9ALMNAHPGD | |
| SCHEMBL11462319 | 0.73 | PYCR1 (0.46) | MAPTNPC1RAB9ALMNAHPGD | |
| SCHEMBL12320858 | 0.73 | GABRA1 (0.36) | MAPTGABRA1GABRB2HTR2A | |
| SCHEMBL8252272 | 0.73 | PYCR1 (0.46) | GABRA1GABRB2 | |
| SCHEMBL20344540 | 0.73 | TYR (0.41) | MAPTNPC1RAB9ALMNAHTT | |
| SCHEMBL31424440 | 0.73 | HPGD (0.34) | MAPTLMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL23586646 | 0.73 | CHRNB2 (0.40) | MAPTLMNAHPGDHTTGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | disclosed |