Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28936580 | 0.89 | GPR139 (0.39) | GPR139UGCGPDE2AKDM4EVNN1 | |
| SCHEMBL28711084 | 0.89 | KDM4E (0.41) | GPR139UGCGPDE2AKDM4EVNN1 | |
| SCHEMBL28715382 | 0.88 | GPR139 (0.42) | GPR139UGCGKDM4EVNN1TP53 | |
| SCHEMBL28700428 | 0.86 | GPR139 (0.41) | GPR139UGCGKDM4EVNN1TP53 | |
| SCHEMBL28715439 | 0.84 | GPR139 (0.41) | GPR139UGCGKDM4EVNN1TP53 | |
| SCHEMBL28700452 | 0.83 | TRPM8 (0.43) | GPR139MRGPRX4PDE2ATRPM8 | |
| SCHEMBL28700451 | 0.83 | TRPM8 (0.43) | GPR139MRGPRX4PDE2ATRPM8 | |
| SCHEMBL28719378 | 0.83 | GPR139 (0.40) | GPR139UGCGKDM4EVNN1TP53 | |
| SCHEMBL28700426 | 0.78 | KDM4E (0.47) | KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL22952693 | 0.76 | GPR139 (0.43) | GPR139UGCGPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206830-A | Alcohol derivatives as Kv7 potassium channel openers | H.隆德贝克有限公司 | 2022-03-18 | — | — | CN | disclosed |