Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 7/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | UGCG | Q16739 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952693 | 1.00 | GPR139 (0.43) | GPR139GABRB1GABRB2PDE2ACTSS | |
| SCHEMBL28936581 | 0.89 | GABRB1 (0.43) | GPR139GABRB1GABRB2PDE2ACTSS | |
| SCHEMBL29440427 | 0.89 | GPR139 (0.42) | GPR139GABRB1GABRB2PDE2ACTSS | |
| SCHEMBL22952643 | 0.89 | GABRB1 (0.43) | GPR139GABRB1GABRB2PDE2ACTSS | |
| SCHEMBL21272633 | 0.89 | GPR139 (0.42) | GPR139GABRB1GABRB2PDE2ACTSS | |
| SCHEMBL21272631 | 0.89 | GPR139 (0.42) | GPR139GABRB1GABRB2PDE2ACTSS | |
| SCHEMBL29440442 | 0.88 | GPR139 (0.45) | GPR139GABRB1GABRB2PDE2ACTSS | |
| SCHEMBL21272669 | 0.88 | GPR139 (0.45) | GPR139GABRB1GABRB2PDE2ACTSS | |
| SCHEMBL21272671 | 0.88 | GPR139 (0.45) | GPR139GABRB1GABRB2PDE2ACTSS | |
| SCHEMBL22952673 | 0.87 | GPR139 (0.41) | GPR139GABRB1GABRB2PDE2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206830-A | Alcohol derivatives as Kv7 potassium channel openers | H.隆德贝克有限公司 | 2022-03-18 | — | — | CN | disclosed |