Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 9/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719536 | 0.88 | HTR6 (0.43) | PKMHTR6POLB | |
| SCHEMBL28700640 | 0.77 | HTR6 (0.44) | PKMHTR6HTR1ADRD3 | |
| SCHEMBL28715559 | 0.76 | PKM (0.45) | PKMNPC1RAB9AHTR6POLB | |
| SCHEMBL28719535 | 0.75 | PKM (0.34) | PKMHTR6KMT2A | |
| SCHEMBL28715570 | 0.71 | GRM4 (0.37) | PKMHTR6KMT2ASMN1; SMN2 | |
| SCHEMBL28716232 | 0.68 | HTR6 (0.51) | HTR6KMT2A | |
| SCHEMBL28711241 | 0.66 | HTR6 (0.40) | PKMHTR6 | |
| SCHEMBL4556004 | 0.64 | PKM (0.71) | PKMNPC1RAB9APOLB | |
| Methane SCHEMBL5097714 | 0.64 | PKM (0.49) | PKMNPC1RAB9APOLBKMT2A | |
| SCHEMBL4901574 | 0.64 | PKM (0.49) | PKMNPC1RAB9APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114105962-A | Compound containing sulfonamide structure, preparation method and application thereof, and pharmaceutical composition and application thereof | 南京烁慧医药科技有限公司 | 2022-03-01 | — | — | CN | disclosed |