Phthalimide

Phthalimide

SCHEMBL28707017

COC(C)OC.O=C1NC(=O)c2ccccc21

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.62
CASP3 P42574 3/20 0.59
CASP7 P55210 2/20 0.59
CASP6 P55212 2/20 0.59
CASP8 Q14790 2/20 0.59
CASP2 P42575 1/20 0.59
CDC25B P30305 3/20 0.50
LMNA P02545 3/20 0.50
ALDH1A1 P00352 3/20 0.50
MAPT P10636 3/20 0.50
CDC25A P30304 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KDM4E B2RXH2 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
HPGD P15428 2/20 0.50
BLM P54132 2/20 0.50
MAP2K7 O14733 1/20 0.50
GMNN O75496 1/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL23063638 0.79 GSK3B (0.88) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL10192661 0.79 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL7771670 0.79 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL30125197 0.79 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL11040503 0.79 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL64 0.79 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL29366030 0.79 GSK3B (1.00) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL1890816 0.79 GSK3B (0.56) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL11706623 0.77 GSK3B (0.83) GSK3BCASP3CASP7CASP6CASP8
Phthalimide SCHEMBL165345 0.77 GSK3B (0.94) GSK3BCASP3CASP7CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113956166-A Method for producing aminoacetaldehyde dimethyl acetal 上海鸣谦化工技术服务中心 2022-01-21 CN claimed
CN-113956166-A Method for producing aminoacetaldehyde dimethyl acetal 上海鸣谦化工技术服务中心 2022-01-21 CN disclosed
CN-113956166-A Method for producing aminoacetaldehyde dimethyl acetal 上海鸣谦化工技术服务中心 2022-01-21 CN disclosed