Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29084494 | 0.82 | GAA (0.33) | CLK1MAPK1NPSR1RXFP1MAPT | |
| SCHEMBL18940228 | 0.82 | ESR1 (0.38) | MAPTMEN1KMT2A | |
| SCHEMBL29084507 | 0.78 | SLC6A4 (0.37) | MAPTPSMB8PDE3BPDE3A | |
| SCHEMBL29084469 | 0.77 | DRD2 (0.40) | TSHRPPARG | |
| SCHEMBL3531804 | 0.76 | TSHR (0.40) | MAPK1NPSR1RXFP1MAPTMEN1 | |
| SCHEMBL15953126 | 0.72 | ESR1 (0.54) | APPCLK1CDK4CCND1MAPK1 | |
| SCHEMBL21798536 | 0.71 | TSHR (0.45) | CLK1MAPK1NPSR1RXFP1MAPT | |
| SCHEMBL28957412 | 0.69 | HAO1 (0.36) | MIF | |
| SCHEMBL21176622 | 0.68 | ESR1 (0.52) | APPCLK1EGFRMAPK1NPSR1 | |
| SCHEMBL15953834 | 0.68 | TUBB4A (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177554-B | Combination therapy for the treatment of cancer | G1治疗公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-108699024-B | Benzothienyl selective estrogen receptor down-regulator compounds | 伊利诺伊大学评议会 | 2022-03-11 | — | — | CN | disclosed |
| CN-108495628-B | Benzothienyl selective estrogen receptor down-modulators | 伊利诺伊大学评议会 | 2022-01-11 | — | — | CN | disclosed |