Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29459506 | 1.00 | ALDH1A1 (0.50) | ALDH1A1NPSR1MAPTTSHRHTT | |
| SCHEMBL1946431 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTTSHRSMN1; SMN2MEN1 | |
| SCHEMBL8449983 | 0.79 | ALDH1A1 (0.47) | ALDH1A1NPSR1MAPTTSHRHTT | |
| SCHEMBL28720658 | 0.78 | L3MBTL1 (0.48) | ALDH1A1NPSR1TSHRHTTCYP1A2 | |
| SCHEMBL9699812 | 0.78 | L3MBTL1 (0.48) | ALDH1A1NPSR1MAPTTSHRHTT | |
| SCHEMBL25911751 | 0.78 | L3MBTL1 (0.66) | ALDH1A1NPSR1MAPTTSHRHTT | |
| SCHEMBL21281664 | 0.77 | L3MBTL1 (0.47) | ALDH1A1NPSR1TSHRHTTCYP1A2 | |
| SCHEMBL1493352 | 0.76 | L3MBTL1 (0.51) | ALDH1A1NPSR1TSHRHTTCYP1A2 | |
| SCHEMBL9798847 | 0.76 | GAA (0.64) | ALDH1A1NPSR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9798916 | 0.76 | TDP1 (0.58) | ALDH1A1NPSR1MAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174303-B | Macrocyclic compounds as STING agonists and methods and uses thereof | 印度鲁宾有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-114174303-A | Macrocyclic compounds as STING agonists, methods and uses thereof | 印度鲁宾有限公司 | 2022-03-11 | — | — | CN | disclosed |