Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214430 | 0.87 | HDAC1 (0.62) | LMNAHPGDTP53HDAC1KMT2A | |
| SCHEMBL9994018 | 0.87 | AOC3 (0.59) | LMNAHPGDTP53CYP2D6MAPK1 | |
| SCHEMBL9994014 | 0.87 | AOC3 (0.59) | LMNAHPGDTP53CYP2D6MAPK1 | |
| SCHEMBL18766237 | 0.85 | KEAP1 (0.50) | LMNAHPGDTP53HDAC1MAPK1 | |
| SCHEMBL1952124 | 0.85 | KEAP1 (0.50) | LMNAHPGDTP53HDAC1MAPK1 | |
| SCHEMBL16965686 | 0.85 | KEAP1 (0.50) | LMNAHPGDTP53HDAC1MAPK1 | |
| SCHEMBL190036 | 0.85 | LMNA (0.48) | LMNAHPGDTP53CYP2D6SRC | |
| SCHEMBL10013666 | 0.85 | DPP4 (0.50) | LMNAHPGDTP53CYP2D6SRC | |
| SCHEMBL571797 | 0.85 | LMNA (0.48) | LMNAHPGDTP53CYP2D6SRC | |
| SCHEMBL16857387 | 0.85 | KEAP1 (0.49) | LMNAHPGDTP53CYP2D6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269794-B | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-114269794-A | Catalyst components for the polymerization of olefins | 巴塞尔聚烯烃意大利有限公司 | 2022-04-01 | — | — | CN | disclosed |