SCHEMBL28707623

SCHEMBL28707623

Cc1ccc(S(=O)(=O)NC(=O)c2ccccc2C(N)=O)cc1

nearest known ligand 0.69

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.69
L3MBTL1 Q9Y468 1/20 0.61
EGFR P00533 3/20 0.59
FLT1 P17948 3/20 0.57
FLT4 P35916 3/20 0.57
KDR P35968 3/20 0.57
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
PTGS2 P35354 5/20 0.56
PTGS1 P23219 1/20 0.56
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
TP53 P04637 1/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 2/20 0.52
HPGD P15428 2/20 0.52
CYP2C9 P11712 1/20 0.52
TDP1 Q9NUW8 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1412654 0.86 POLB (0.71) POLBEGFRFLT1FLT4KDR
SCHEMBL30514016 0.84 FLT1 (0.78) POLBEGFRFLT1FLT4KDR
SCHEMBL1928898 0.84 FLT1 (0.78) POLBEGFRFLT1FLT4KDR
SCHEMBL9618565 0.83 KDM4E (0.77) POLBEGFRFLT1FLT4KDR
SCHEMBL9659192 0.82 FLT1 (0.78) POLBEGFRFLT1FLT4KDR
SCHEMBL9414560 0.81 POLB (0.68) POLBL3MBTL1EGFRFLT1FLT4
SCHEMBL9177675 0.79 POLB (0.66) POLBEGFRFLT1FLT4KDR
SCHEMBL15821566 0.79 LMNA (0.67) POLBL3MBTL1KMT2ACA1CA2
SCHEMBL10438385 0.79 POLB (0.65) POLBEGFRFLT1FLT4KDR
SCHEMBL39499 0.78 KDM4E (0.55) POLBL3MBTL1FLT1FLT4KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113429700-B Polyvinyl chloride foam with uniform foam pores and preparation method thereof 东营瑞致新材料有限公司 2022-06-10 CN disclosed
CN-113429700-B Polyvinyl chloride foam with uniform foam pores and preparation method thereof 东营瑞致新材料有限公司 2022-06-10 CN disclosed
CN-113429700-A Polyvinyl chloride foam with uniform foam pores and preparation method thereof 东营瑞致新材料有限公司 2021-09-24 CN disclosed
CN-113429700-A Polyvinyl chloride foam with uniform foam pores and preparation method thereof 东营瑞致新材料有限公司 2021-09-24 CN disclosed