Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | FLT1 | P17948 | 3/20 | 0.59 |
| ▸ | FLT4 | P35916 | 3/20 | 0.59 |
| ▸ | KDR | P35968 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16244081 | 0.91 | KDM4E (0.62) | POLBGAAFLT1FLT4KDR | |
| SCHEMBL7797528 | 0.89 | GAA (0.59) | POLBGAAFLT1FLT4KDR | |
| SCHEMBL16634981 | 0.87 | GAA (0.57) | POLBGAAFLT1FLT4KDR | |
| SCHEMBL26161946 | 0.86 | GAA (0.56) | POLBGAAFLT1FLT4KDR | |
| SCHEMBL28129967 | 0.86 | GAA (0.60) | POLBGAAFLT1FLT4KDR | |
| SCHEMBL18803129 | 0.86 | POLB (0.64) | POLBGAAFLT1FLT4KDR | |
| SCHEMBL3302654 | 0.86 | FLT1 (0.57) | POLBGAAFLT1FLT4KDR | |
| SCHEMBL27650215 | 0.86 | GAA (0.55) | POLBGAAFLT1FLT4KDR | |
| SCHEMBL7794431 | 0.85 | MEN1 (0.58) | POLBGAAFLT1FLT4KDR | |
| SCHEMBL15495162 | 0.84 | RXFP1 (0.60) | POLBGAAFLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0043630-B1 | IMPROVED PROCESS FOR THE SILYLATION OF ORGANIC COMPOUNDS WITH 1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE BY MEANS OF CATALYSIS WITH CERTAIN NITROGEN CONTAINING COMPOUNDS | GIST-BROCADES N.V. (NL) | 1986-01-08 | — | — | EP | claimed |
| US-4400509-A | WITH HEXAMETHYLDISILANE WITH AN ORGANONITROGEN CATALYST | GIST-BROCADES N.V. (NL) | 1983-08-23 | — | — | US | claimed |
| EP-0043630-A2 | Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds | GIST-BROCADES N.V. (NL) | 1982-01-13 | — | — | EP | claimed |
| CN-111517996-B | Preparation method and preparation intermediate of benzoyl sulfamoyl benzamide | 河北兰升生物科技有限公司 | 2023-08-15 | — | — | CN | disclosed |
| CN-111517996-A | Preparation method and preparation intermediate of benzoyl sulfamoyl benzamide | 河北兰升生物科技有限公司 | 2020-08-11 | — | — | CN | disclosed |
| EP-0611770-A2 | A process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1994-08-24 | — | — | EP | disclosed |
| US-5084568-A | Process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1992-01-28 | — | — | US | disclosed |
| US-5013854-A | Process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0381451-A1 | A process for preparing acid halides | ELI LILLY AND COMPANY (US) | 1990-08-08 | — | — | EP | disclosed |
| EP-0043630-B1 | IMPROVED PROCESS FOR THE SILYLATION OF ORGANIC COMPOUNDS WITH 1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE BY MEANS OF CATALYSIS WITH CERTAIN NITROGEN CONTAINING COMPOUNDS | GIST-BROCADES N.V. (NL) | 1986-01-08 | — | — | EP | disclosed |
| EP-0047560-B1 | PROCESS FOR THE PREPARATION OF 7-ACYLAMINO-3-(THIO-SUBSTITUTED)METHYL-3-CEPHEM-4-CARBOXYLIC ACID 1-OXIDE DERIVATIVES | GIST-BROCADES N.V. (NL) | 1985-04-10 | — | — | EP | disclosed |
| US-4400509-A | WITH HEXAMETHYLDISILANE WITH AN ORGANONITROGEN CATALYST | GIST-BROCADES N.V. (NL) | 1983-08-23 | — | — | US | disclosed |
| US-4379923-A | Preparation of 7-acylamino-3-(thio-substituted)-methyl 3-cephem-4-carboxylic acid-1-oxide derivatives | GIST-BROCADES N.V. (NL) | 1983-04-12 | — | — | US | disclosed |
| EP-0047560-A2 | Process for the preparation of 7-acylamino-3-(thio-substituted)methyl-3-cephem-4-carboxylic acid 1-oxide derivatives | GIST-BROCADES N.V. (NL) | 1982-03-17 | — | — | EP | disclosed |
| EP-0043630-A2 | Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds | GIST-BROCADES N.V. (NL) | 1982-01-13 | — | — | EP | disclosed |