Sugi Predict

Sugi Predict / Compounds / SCHEMBL39499

SCHEMBL39499

SCHEMBL39499

NC(=O)c1ccc(S(=O)(=O)NC(=O)c2ccccc2C(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.55
▸ KAT6A Q92794 1/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ LMNA P02545 1/20 0.54
▸ HPGD P15428 1/20 0.54
▸ FLT1 P17948 5/20 0.51
▸ FLT4 P35916 5/20 0.51
▸ KDR P35968 5/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ POLB P06746 2/20 0.49
▸ GAA P10253 1/20 0.49
▸ P4HTM Q9NXG6 2/20 0.48
▸ CA1 P00915 2/20 0.47
▸ CA2 P00918 2/20 0.47
▸ CA9 Q16790 2/20 0.47
▸ BCL2L1 Q07817 1/20 0.47
▸ MCL1 Q07820 1/20 0.47
▸ PTGS1 P23219 1/20 0.46
▸ PTGS2 P35354 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10765828 0.86 KDM4E (0.72) KDM4EMEN1KMT2ALMNAHPGD
SCHEMBL376340 0.84 MEN1 (0.73) KAT6AMEN1KMT2ALMNAFLT1
SCHEMBL12489988 0.83 MEN1 (0.66) KDM4EKAT6AMEN1KMT2ALMNA
SCHEMBL1412654 0.82 POLB (0.71) KDM4EMEN1KMT2ALMNAHPGD
SCHEMBL18803129 0.81 POLB (0.64) KAT6ALMNAFLT1FLT4KDR
SCHEMBL25424924 0.81 BCL2L1 (0.70) MEN1KMT2ALMNAFLT1FLT4
SCHEMBL28707623 0.78 POLB (0.69) KDM4EMEN1KMT2ALMNAHPGD
SCHEMBL4638239 0.76 CA2 (0.59) KAT6AMEN1KMT2ALMNAFLT1
SCHEMBL18132521 0.75 ALDH1A1 (0.71) MEN1KMT2AL3MBTL1POLBGAA
Phthalic Acid SCHEMBL30112901 0.75 MAPT (0.76) KDM4EHPGDL3MBTL1POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11185075-B2 Herbicidal phenyltriazolinones BASF SE (DE) 2021-11-30 — — US claimed
EP-3555053-B1 HERBICIDAL PHENYLTRIAZOLINONES BASF SE (DE) 2021-02-17 — — EP claimed
US-20200085052-A1 Herbicidal Phenyltriazolinones BASF SE (DE) 2020-03-19 — — US claimed
EP-3555053-A1 HERBICIDAL PHENYLTRIAZOLINONES BASF SE (DE) 2019-10-23 — — EP claimed
WO-2018108695-A1 HERBICIDAL PHENYLTRIAZOLINONES BASF SE (DE) 2018-06-21 — — WO claimed
US-20160295866-A1 COMPOSITION OF 1,5-DIMETHYL-6-THIOXO-3-(2,2,7-TRIFLUORO-3-OXO-4-(PROP-2-YNYL)-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-YL)-1,3,5-TRIAZINANE-2,4-DIONE BASF SE (DE) 2016-10-13 — — US claimed
EP-3068225-A1 COMPOSITION OF 1,5-DIMETHYL-6-THIOXO-3-(2,2,7-TRIFLUORO-3-OXO-4-(PROP-2-YNYL)-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-YL)-1,3,5-TRIAZINANE-2,4-DIONE BASF SE (DE) 2016-09-21 — — EP claimed
EP-2496573-B1 HERBICIDAL TETRAHYDROPHTHALIMIDES BASF SE (DE) 2015-07-01 — — EP claimed
WO-2015071087-A1 COMPOSITION OF 1,5-DIMETHYL-6-THIOXO-3-(2,2,7-TRIFLUORO-3-OXO-4-(PROP-2-YNYL)-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-YL)-1,3,5-TRIAZINANE-2,4-DIONE BASF SE (DE) 2015-05-21 — — WO claimed
US-8445407-B2 Herbicidal tetrahydrophthalimides BASF SE (DE) 2013-05-21 — — US claimed
EP-2443102-B1 HERBICIDAL BENZOXAZINONES BASF SE (DE) 2013-04-17 — — EP claimed
US-20240240197-A1 HERBICIDE-TOLERANT PLANTS BASF SE (DE) 2024-07-18 — — US disclosed
EP-4398886-A1 NEW MICROPARTICLES CONTAINING ACTIVE SUBSTANCES BASF SE (DE) 2024-07-17 — — EP disclosed
EP-4396163-A1 HERBICIDAL MALONAMIDES CONTAINING MONOCYCLIC HETEROAROMATIC RINGS BASF SE (DE) 2024-07-10 — — EP disclosed
EP-4396173-A1 HERBICIDAL MALONAMIDES CONTAINING A CONDENSED RING SYSTEM BASF SE (DE) 2024-07-10 — — EP disclosed
WO-2011028833-A2 HERBICIDE-TOLERANT PLANTS BASF AGROCHEMICAL PRODUCTS, B.V. (NL) 2011-03-10 — — WO disclosed
WO-2011028836-A2 HERBICIDE-TOLERANT PLANTS BASF AGROCHEMICAL PRODUCTS.B.V. (NL) 2011-03-10 — — WO disclosed
WO-2010145992-A1 HERBICIDAL BENZOXAZINONES BASF SE (DE) 2010-12-23 — — WO disclosed
US-20100173777-A1 Piperazine Compounds Having Herbicidal Action BASF SE (DE) 2010-07-08 — — US disclosed
US-20100152047-A1 Piperazine Compounds Whith a Herbicidal Action BASF SE (DE) 2010-06-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11185075-B2 Herbicidal phenyltriazolinones DDT, UPP1, UMPS KDM4E 1359/4885KAT6A 4405/4885MEN1 4865/4885
US-20200085052-A1 Herbicidal Phenyltriazolinones DDT, UPP1, UMPS KDM4E 1359/4885KAT6A 4405/4885MEN1 4865/4885
US-20100152047-A1 Piperazine Compounds Whith a Herbicidal Action CBR3, CBR1, CNPY2 KDM4E 4015/4885KAT6A 3028/4885MEN1 4546/4885
US-20160295866-A1 COMPOSITION OF 1,5-DIMETHYL-6-THIOXO-3-(2,2,7-TRIFLUORO-3-OXO-4-(PROP-2-YNYL)-3,4-DIHYDRO-2H-BENZO[B][1,4]OXAZIN-6-YL)-1,3,5-TRIAZINANE-2,4-DIONE TXN2, COX5A, PRDX5 KDM4E 697/4885KAT6A 1789/4885MEN1 4176/4885
US-20100173777-A1 Piperazine Compounds Having Herbicidal Action CBR3, CBR1, CNPY2 KDM4E 4069/4885KAT6A 3312/4885MEN1 4548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.