Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28707698 | 0.95 | MAPT (0.54) | FAAHSMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL28715966 | 0.89 | ALDH1A1 (0.55) | FAAHSMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL28718272 | 0.88 | ACHE (0.48) | FAAHSMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL29670963 | 0.88 | HDAC1 (0.50) | FAAHSMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL28715967 | 0.88 | HDAC1 (0.50) | FAAHSMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL29670962 | 0.88 | ALDH1A1 (0.58) | FAAHSMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL28714009 | 0.88 | ALDH1A1 (0.58) | FAAHSMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL28705611 | 0.86 | HDAC1 (0.50) | FAAHSMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL29670989 | 0.86 | HDAC1 (0.50) | FAAHSMN1; SMN2NPC1NFKB1RAB9A | |
| SCHEMBL28718309 | 0.86 | BRD4 (0.47) | SMN1; SMN2MAPTBRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114276303-B | Ureido compounds or pharmaceutically acceptable salts thereof, and preparation method and application thereof | 河南大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-114276303-A | Ureido compound or its medicinal salt and its preparing process and application | 河南大学 | 2022-04-05 | — | — | CN | disclosed |